Table 4 Type and frequency of immunophenotypic aberrancies detected in PB neutrophils from LR-MDS patients versus normal individuals (controls)
|
LR-MDS (n = 14) |
Controls (n = 14) | |||
|---|---|---|---|---|
| Decreased | Increased | Decreased | Increased | |
| Abnormal light scatter characteristics | ||||
| FSC | 10 (71%) | 1 (7%) | 0 (0%) | 0 (0%) |
| SSC | 8 (57%) | 0 (0%) | 0 (0%) | 1 (7%) |
| Abnormal expression of cell surface markers | ||||
| CD10 | 9 (64%) | 1 (7%) | 0 (0%) | 0 (0%) |
| CD11b | 10 (71%) | 1 (7%) | 0 (0%) | 1 (7%) |
| CD11c | 10 (71%) | 0 (0%) | 0 (0%) | 0 (0%) |
| CD13 | 4 (29%) | 1 (7%) | 0 (0%) | 0 (0%) |
| CD15 | 0 (0%) | 0 (0%) | 1 (7%) | 1 (7%) |
| CD16 | 6 (43%) | 0 (0%) | 0 (0%) | 0 (0%) |
| CD45 | 2 (14%) | 1 (7%) | 1 (7%) | 0 (0%) |
| Number of individuals with abnormal parameters | ||||
| No abnormal parameters | 1 (7%) | 10 (71%) | 12 (86%) | 11 (79%) |
| One abnormal parameter | 0 (0%) | 3 (21%) | 2 (14%) | 3 (21%) |
| Two abnormal parameters | 2 (14%) | 1 (7%) | 0 (0%) | 0 (0%) |
| Three abnormal parameters | 1 (7%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Four abnormal parameters | 3 (21%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Five abnormal parameters | 4 (29%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Six abnormal parameters | 2 (14%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Seven abnormal parameters | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Eight abnormal parameters | 1 (7%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Nine abnormal parameters | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |